O2 and glutathione effects on water radiolysis: a simulation study - IN2P3 - Institut national de physique nucléaire et de physique des particules
Communication Dans Un Congrès Année : 2011

O2 and glutathione effects on water radiolysis: a simulation study

Résumé

We present a MC simulation of water radiolysis when O2 and glutathione are present in the solution. Our simulation is based on the continuum approximation proposed by Green and co-workers'. We investigate in particular the sensitivity of the yield of HO2•+O2−• to the concentration of O2 and glutathione and to the LET of the ionising radiation. We demonstrate that the production of HO2•/O2−• is highly sensitive to these parameters and that the variation of their yield with the O2 concentration shares remarkable similarities with the O2 effect reported for biological cell damage efficiency .

Dates et versions

in2p3-00575571 , version 1 (10-03-2011)

Identifiants

Citer

A. Colliaux, B. Gervais, C. Rodriguez-Lafrasse, M. Beuve. O2 and glutathione effects on water radiolysis: a simulation study. COST Chemistry CM0603–MELUSYN Joint Meeting, Mar 2010, Paris, France. pp.012007, ⟨10.1088/1742-6596/261/1/012007⟩. ⟨in2p3-00575571⟩
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